I am sure you all heard about the three doshas Vata, Pitta and Kapha.
But have you heard of the term Dhatus? Dhatus denotes the structural components of the body.
The definition of dhatu is:
Deha dharanat dhatavah- They support the body.
If the Dhatus/ body tissue get vitiated they are called as dushyas (as the get vitiated by the doshas).
We have to remember that there is no disease without a dosha (Vata/ Pitta/ Kapha) imbalance.